New Insights on Coding Mutations and mRNA Levels of Candidate Genes Associated with Diarrhea Susceptibility in Baladi Goat
نویسندگان
چکیده
The purpose of this investigation was to examine mutations and mRNA levels potential genes linked diarrhea susceptibility in order assess the health status diarrheic kids Baladi goats. One hundred female (35 65 apparently healthy) were used. PCR-DNA sequencing conducted for TMED1, CALR, FBXW9, HS6ST3, SMURF1, KPNA7, FBXL2, PIN1, S1PR5, ICAM1, EDN1, MAPK11, CSF1R, LRRK1, CFH markers revealed nucleotide sequence variants frequency distribution all detected SNPs (p ˂ 0.05) between healthy affected kids. Chi-square analysis showed a significant difference resistant animals. Gene expression profile that CSF1R LRRK1 significantly up-regulated than ones. Meanwhile, gene elicited an opposite trend. On examined indicators, there substantial interaction type resistance/susceptibility. findings could support importance variations pattern as biomarkers resistance/susceptibility offer useful management strategy
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ژورنال
عنوان ژورنال: Agriculture
سال: 2023
ISSN: ['2077-0472']
DOI: https://doi.org/10.3390/agriculture13010143